17 article(s) found.
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Classification of epileptic seizures and epilepsy syndromes [2013] - 187KB
by BI Lee
The efforts of ILAE for providing a standardized classification and terminology of epileptic seizures and epilepsy syndrome; the international classification of epileptic seizures in 1981 and internat...

Animal models of early life seizures and epilepsies [2013] - 133KB
by MJ Gygax, SL Moshé
Epilepsy can occur throughout the human life span, with peaks during early life and senescense/ageing. During development, epilepsy is often but not always diagnosed in association with cognitive and ...

Using experimental models to provide insights into mechanism of genetic generalised epilepsy [2013] - 147KB
by K Yamakawa
EFHC1 gene mutations have been described in patients with juvenile myoclonic epilepsy (JME) and other types of idiopathic generalized epilepsy. We generated Efhc1-deficient mouse and found that the mo...

Ion channels: genetics and as a targets for antiepileptic drugs [2013] - 144KB
by K Yamakawa
Dravet syndrome is caused by mutations of the SCN1A gene that encodes voltage-gated sodium channel alpha-1 subunit. SCN1A-knock-in mouse with a disease-relevant nonsense mutation that we generated rep...

Death in epilepsy: is it preventable? [2013] - 147KB
by JW Dunne
The risk of premature death is higher in people with epilepsy, but many other factors have a potentially bigger role than epilepsy and its treatment. Most people with epilepsy will not die as a direct...

EEG monitoring in the intensive care unit [2013] - 162KB
by JW Dunne
Performing EEG in the intensive care unit (ICU) has many technical, environmental and resourcerelated challenges. Recording audio and video with EEG is always preferable for recognising artifacts and ...

Application of PET and SPECT in epilepsy [2013] - 591KB
by Y Chinvarun
PET and SPECT are valuable clinical tools in the management of patients with medically resistant, partial epilepsy who are under evaluation for surgical treatment. The value of PET for localization of...

Pharmacogenomics screening of HLA-B*1502 in epilepsy patients: How we do it in the UKM Medical Centre, Malaysia [2013] - 159KB
by SM Then, ZZM Rani, AA Raymond, R Jamal
Previous studies have shown that carbamazepine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) patients is associated with the HLA-B*1502 allele. Screening for HLA-B*1502 b...

Delivery, breast feeding and child rearing in women with epilepsy [2013] - 153KB
by LIC Lim
The occurrence of seizures during delivery is very low and convulsive status epilepticus is rare. Seizure freedom for at least 9 months prior to pregnancy is associated with a high likelihood of remai...

Psychiatric comorbidity in patients with epilepsy [2013] - 124KB
by SP Park
People with epilepsy have a higher risk of developing psychiatric problems than the general population. The degree of affective symptoms such as depression and anxiety was affected by seizure control ...

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